Initially, Shu is rather cowardly and has a very low opinion of himself. There are hints that he may have some kind of disorder, as he notes that his mind might be out of step with everyone else's, though nothing concrete is ever confirmed. He also has trouble making eye contact with people, saying that when he does, he gets nervous and forgets what he was going to say. He can also be rather apathetic and self-absorbed when scolded for making a carelessly cold remark, he can only think about his own feelings that got hurt instead of feeling bad about what he said. Just about everyone calls him out for his inability to read between the lines, from Hare, his friend at school, to Kenji, a mass murderer responsible for an infamous terrorist bombing.

In fact, at the start of the series, he's only been able to forge 'friendships' by going along with what other people say. He is frequently rude and insensitive, largely because he never knows what to say to others. Initially, Shu is a rather withdrawn person who usually keeps to himself, spending most of his time surfing the net and watching Egoist videos. In Lost Christmas, he appears as a 7 years old child with the same features are the main story, except he doesn't have his blond streak and is a cowlick instead, which may hint that his streak is dyed. Shu may have been blind in the epilogue, because if you look at his ears in the start of the series and the end you can see he has something in ears unlike all the other characters and in the middle of the series when he had the void his eyesight may have been fixed. Shu's hair greatly resembles his father, Kurosu's. Also, he gained the Apocalypse Virus on the right side of his face (1st Stage of Apocalypse Virus). In Episode 17, he lost his right arm which was replaced with his Void in Episode 19 after injecting himself with the third Void Genome ampule. Since he acted as the King of japan (motivated after seeing Hare die in his arms), he wore a green coat, a scarf, a white t-shirt, black pants, and a chain. For his time with the Undertakers, he wore their standard uniform.

He has brown hair with a blond streak forming from the crown and maroon/red eyes that occasionally appear blood-red. He is usually seen wearing his school uniform.

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